LC-MS

On-demand webinar: Addressing the “Identity Crisis” in Small Molecule Compound Identification with Mass Spectrometry

Determining the chemical structure for the majority of compounds “identified” in a typical untargeted analysis remains a stubborn challenge and a persistent logjam, holding up progress in many fields including metabolomics, metabolism studies, forensics, clinical research, environmental and food safety, contaminant analysis, and E&L identification. This webinar describes a fundamental new approach to untargeted small […]

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Confident quantitation. Any compound. Any Matrix. Any User.

Achieve your business and scientific goals Easily answer critical analytical challenges during targeted quantitation workflows in your laboratory. With its segmented quadrupoles, faster rod drivers, and improved electron multipliers, the Thermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer is the workhorse delivering unprecedented robustness with best-in-class sensitivity for everyday use and for every user.   […]

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Celebrate the holiday season with safe food

Food analytical testing information   Ensuring the safety of the world’s food supply is critical. At any point in the process, products may become contaminated and unfit for consumption. Whether you are ensuring regulatory compliance or enhancing nutrition, our food safety testing solutions strengthen the entire food chain so you can deliver the uncompromised food […]

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New pharmaceutical extractables & leachables, or food contact materials resources

Various materials are used throughout the food & drug manufacturing and packaging chain and can give rise to migration (leaching) where chemical substances and metals can transfer to the product. Packaging can be constructed from any one of a diverse range of plastics, paper and board, composites, glass, metal, or cork. Regulations are complex, but […]

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Use the cleanest SPE to get the best analytical results! Test now and experience our awesome quality.

Are you convinced that you are using the best possible Solid Phase Extraction in your lab gaining the cleanest extracts and the best concentration factor? Test our unique Solid Phase Extraction (SPE) products now! Request free test packs   Are you using GC in your lab? If your method of detection is GC or GCMS, […]

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Five Additional Pharmaceutical Impurity Questions

isq-ec-single-quad-ms

Over the past two months, and during our recent pharmaceutical impurity workshop in Switzerland with LGC Standards, we’ve been asked some additional questions related to pharmaceutical impurities. In this article, we answer an additional five questions: 1. How is the topic of extractables and leachables related to pharmaceutical impurities? The topics are very closely related […]

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Webinar: Top & Middle-Down ADC Characterization

Peptide mapping is the gold standard for in-depth characterization of biotherapeutics; however, sample preparation, LC runtime and data analysis can be labor intensive and time consuming. Top or middle-down mass spectrometry experiments show promise as an alternate technique for primary order structure confirmation. However, historically top or middle-down characterization has been limited by bottlenecks in […]

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Why the Q Exactive UHMR Mass Spectrometer Is Needed by Cryo-EM Users to Achieve a Complete and Accurate 3D Structure

To understand protein function and mechanism of action, it is essential to determine protein complex assembly and structure. Solving the structure of large dynamic complexes often requires integrating several complementary techniques, such as mass spectrometry(MS), traditional XRD, NMR, cryo-electron microscopy(cryo-EM) and computational modeling—an approach known as integrative structural biology [1]. The primary advantage of cryo-EM is its […]

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Meeting the Biotin Challenge with Mass Spectrometry

Nowadays, people are using a lot of nutritional and dietary supplements. Influence from social media, high drug prices, and the burden of hectic lifestyles are compelling consumers to try supplements as alternatives to prescribed drugs. Global supplement annual sales reached $121.2 Billion in 2016, with 5.7 percent growth over the previous year, with the market primarily driven […]

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